PDF Layers allow you to turn on (from within Adobe Reader) only the size(s) that you want to print. This gives the best of both worlds of nested patterns and single-size patterns. Titchy Threads was the first pattern company to introduce this feature.
To see the layers in a PDF, click the Layers button on the left.
You will need to choose "List Layers for All Pages" then select the size(s) that you wish to print.
Now you can turn off all the sizes except for the one you want to print.